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succinic acid pka

Additionally, succinate decreases cardiomyocyte viability through a caspase-3 activation pathway, effect also prevented by PKA inhibition. The total number of non-confidential registered compositions submitted in REACH dossiers are displayed here. Registrants can choose from the following picklist endpoint conclusions/effect levels: Respiratory irritation provides substance information on the substance’s irritation effect on the respiratory system. While it is present in the final substance, it was not intentionally added. Pour density provides substance information on the pour density in grams per millilitre at a temperature measured in °C. Oxidising. Data from all dossiers registered and the Classifications and Labelling Inventory (C&L) for the same substance are used to generate the Brief Profile. minadepiedras.com. LC50 for marine water algae provides substance information on the substance’s lethal concentration for 50% of the marine water algae in the test, generally displayed in milligram per litre. Thirdly the display of data is prioritised by units. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. The succinic acid market is a capital–intensive market, and the downtime involved with the penetration of succinic acid as an intermediate to the existing material/application also causes significant loss to the end-use industries. This section summarises the values related to adsorption/desorption from all registered dossiers for the substance. The dark blue bar illustrates the percentage of matching substance classifications provided by manufacturers and importers in a REACH registration dossier. To confirm if a substance is covered by a specific legislative framework the official publication should be consulted.Reproduction or further distribution of this information may be subject to copyright protection. Registration – indicated if there is at least one dossier registered and disseminated for the substance, how many non-confidential registrations are active and/or inactive and the type of submissions (joint and/or individual). Note: Registrants can also select ‘other’ as the type of Henry’s law constant. IUPAC names gives all the non-confidential names provided to ECHA in submissions under REACH, CLP, BPR and PIC, where indicated to be a IUPAC name. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’. ChEBI. BOD5*100/ThOD provides substance information on the substance’s BOD5*100/ThOD values displayed in O2 (milli)gram per gram test material. CAS No. Succinic acid, also called Butanedioic Acid, a dicarboxylic acid of molecular formula C 4 H 6 O 4 that is widely distributed in almost all plant and animal tissues and that plays a significant role in intermediary metabolism. Succinic acid is byproduct of sugar fermentation, and is present in wines and beer. EC10 / LC10 or NOEC for microorganisms provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested microorganisms or the no observed effect concentration for microorganisms. See ‘Data for workers – Inhalation exposure’, with the following additional hazard assessment conclusion in the case of short term: The registered threshold is generally displayed in milligrams per kilogram per bodyweight per day. See information under ‘Study results oral’. The quality and correctness of the information remains the responsibility of the data submitter. Succinic Acid 99,7. If additional information derived from classification and labelling (C&L) notifications to ECHA under the CLP Regulation exists, this will be displayed below the information derived from harmonised classification and labelling and REACH registrations. EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. Aliquam nec erat semper, suscipit libero et, bibendum mauris. Succinic acid, when produced through fermentation, converts glucose to succinic acid along a portion of the reductive cycle of the tricarboxylic acid (TCA) cycle [Lee et al.,2002].Figure 2-3 depicts the reactions and enzymes in a typical fermentation process that transforms glucose to succinic acid. Numele provine din limba latină succinum (chihlimbar), din care poate fi obținut acidul. The Index number for each substance is in the form of a digit sequence of the type ABC-RST-VW-Y. Translated names gives the names in different EU languages, where available to ECHA. The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. If there are additives and impurities relevant for the substance classification, these are also indicated. Succinic acid, H2C4H4O4, is a weak diprotic acid, pKa1 = 4.21 and pKa2 = 5.64 at 25 degrees celsius.).? If so, the data provided is not processed for the Brief Profile. Additionally, if registrants select ‘other’ as a unit of measure for pressure, the measurement conditions (and therefore the study results) cannot be processed in the Brief Profile. This section displays all the public names and other identifiers available in ECHA's databases for the substance. This section summarises the values related to biodegradation in soil from all registered dossiers for the substance. The % is based on count of values provided. This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications. Applicant’s summary and conclusion – Interpretation of results. 1 000 g will be displayed as 1 kg. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter). Its pKa at 25°C are 4.21 and 5.64 . This main layer contains sublayers for the chemical formula, atom connections and hydrogen atoms. This brief profile is covered by the ECHA Legal Notice. If not, check our Amber Healing Properties post, to learn more about amber and the way it influences human body. For substance’s physical state at 20°C and 1 013 hPa, registrants can classify their substance as: For substance’s form, registrants can classify their substance as: For substance’s odour, registrants can classify their substance as: For substance’s type, registrants can classify their substance as: Summary data is collected from the endpoint summary(ies) provided by registrants of REACH dossiers. More information on CLH can be found here. No or insufficient data available at present, Hazard related to composition of atmosphere identified, No potential to cause toxic effects if accumulated (in higher organisms) via the food chain, bw/day (mg/kg bw/day; mg/kg bw/day; mg/kg bw/day), DMEL (Derived Minimum Effect Level) - not included for short–term effects, Insufficient data available (further information necessary), Hazard unknown (no further information necessary), Hazard unknown but no further hazard information necessary as no exposure expected, ‘No DNEL required: short term exposure controlled by conditions for long-term’ is added, Hamster (combine hamster, Armenian; hamster, Chinese and hamster, Syrian), No adverse effect observed (not irritating), Adverse effect observed (irreversible damage), mg/kg bw/day (nominal/actual dose received), See ‘Study results oral: Prioritization by test species’, mg/L air (combining mg/L air, mg/L air (nominal), mg/L air (analytical), mg/m³ air, mg/m³ air (nominal), mg/m³ air (analytical)), ppm (combine ppm, ppm (nominal), ppm (analytical), mg/kg bw/day (actual dose received), mg/kg bw/day (combining mg/kg bw/day (nominal), mg/kg bw/day (actual dose received) and mg/kg bw/day), mg/cm² per day (combining mg/cm² per day, mg/cm² per day (nominal), mg/cm² per day (analytical)), No study available / no study available (further information necessary). These production facilities could make their process more value-added by using their waste carbon dioxide and biomass, such as cane molasses and cheese whey for succinic acid production. It is a conjugate acid of a methylsuccinate. ABC corresponds to the atomic number of the most characteristic element or the most characteristic organic group in the molecule. This substance is used by consumers, by professional workers (widespread uses), in formulation or re-packing, at industrial sites and in manufacturing. Oxidation reduction potential in mV provides substance information on the substance’s oxidation reduction measured in millivolts at a temperature measured in °C. Values are generally displayed in milligram per litre. Additionally, if available, information on the use of the substance and how consumers and workers are likely to be exposed to it can also be displayed here. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (in hours, longer prioritised over shorter). Table of Acids with Ka and pKa Values* CLAS Acid HA A-Ka pKa Acid Strength Conjugate Base Strength Hydroiodic HI I-Hydrobromic HBr Br-Perchloric HClO4 ClO4-Hydrochloric HCl Cl-Chloric HClO3 ClO3-Sulfuric (1) H2SO4 HSO4-Nitric HNO3 NO3-Strong acids completely dissociate in aq solution (Ka > 1, pKa … Compound Type Concentration; Succinic acid: Solute: 100mM: D2O: Solvent: 100%: sodium phosphate: Buffer: 50mM: sodium azide: Cytocide: 500uM: DSS: Reference: 0.1% Other identifiers gives any other non-name identifiers available for ths substance. Maintaining Guidance on the safe use of the substance provided by manufacturers and importers of this substance. Half-life in water provides substance information on the substance’s half-life in water in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C. The aim is to display the lowest values reported as causing the most adverse effects, and hence the broadest possible safety margins for the substance. Thirdly the display of data is prioritised by units. Nulla pulvinar vitae nunc vitae sagittis. This section summarises the auto flammability values from all registered dossiers for the substance. pH provides substance information on the substance’s acidity level measured in pH at a temperature measured in °C and a concentration measured in (milli)grams per litre. Note: Registrants can also select ‘BMD’, ‘BMC’, ‘dose level’ and ‘conc. This section displays the values related to reproductive toxicity from all registered dossiers for the substance. Vivamus mauris lorem, fringilla at diam a, laoreet consequat eros. If the substance has no EC number attributed, ECHA will attribute a list number. Prioritization by the dose descriptor type: Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above, i.e. Data is generally displayed in milligram per kilo bodyweight. Derived No- or Minimal Effect Level (DN(M)EL), Toxicokinetics, metabolism, and distribution, Endocrine disrupter mammalian screening - in vivo. The use information is displayed per relevant life cycle stage of the substance. It is soluble in water and slightly soluble in ethanol for the preparation of pentaheterocyclic compounds.Specification:Test ItemsSp Additional information on classification and labelling (C&L) – if available – is derived from REACH registration dossiers submitted by industry. 2016). Long-term EC10 or LC10 or NOEC for soil dwelling arthropods provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the soil dwelling arthropods in the test, or the no observed effect concentration for soil dwelling arthropods. LC50 for marine water fish provides substance information on the substance’s lethal concentration for 50% of the marine water fish in the test, displayed in milligram per litre. This substance is used in the following products: pH regulators and water treatment products. For example, an update in a section of a dossier that is not displayed in the Brief Profile will not result in an update of the Brief Profile. The availability of additional data beyond the five results displayed is indicated by (…). E) Sodium succinate and succinic acid (pKa = 4.21) H₂CO₃ and NaHCO₃ (pKa values are 3.77 and 10.4) If 0.1 moles of Na₂HPO₄ and 0.1 moles of NaH₂PO₄ are mixed in water, what is the resulting pH? Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. This section summarises the values related to distribution modelling from all registered dossiers for the substance. At concentration of 10 mM, it has a pH of 3.12. Bioaccumulation factor (terrestrial species) provides substance information on the substance’s terrestrial bioaccumulative properties not taking account the dimensions. 7 The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as critical for human health and/or the environment based on the information provided to the Agency. Other names gives any names of any other type, such as common names, synonyms and acronyms. Units and data are normalised when possible and therefore the unit of measure/order of magnitude in the Brief Profile data may not correspond exactly to the one in the registered dossier. Please see Registrants/Suppliers details. Precautions for using this substance have been recommended by its registrants under REACH, as follows: When handling this substance: wear protective gloves and/or clothing, and eye and/or face protection as specified by manufacturer/supplier. Density provides substance information on the density in grams per (centi)metre at a temperature measured in °C. In case of incident: Immediately call a poison center or doctor/physician. ThOD provides substance information on the substance’s ThOD values displayed in O2 (milli)gram per gram test material. Nitric Acid - HNO. For example, substance impurities can constitute a valid reason for a different classification of the substance. Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or, The (√- check mark)-icon indicates the classification is defined under. Bioaccumulation Factor (aquatic species) L/kg ww provides substance information on the substance’s bioaccumulative properties for aquatic species measured in litre per kilogram  (wet weight). Henry’s Law Constant provides substance information on the substance’s Henry’s Law Constant measured in in Pa.m3.mol-1 at a temperature measured in °C. BOD5*100/COD provides substance information on the substance’s BOD5*100/COD values displayed in O2 (milli)gram per gram test material. Thirdly the display of data is prioritised by unit. The pKa values for succinic acid, pKa 1 = 4.61 and pKa 2 = 5.61, lie below the optimal growth and production pH of many organisms. Values are generally displayed in milligram per litre. This substance is used in the following activities or processes at workplace: closed, continuous processes with occasional controlled exposure, closed batch processing in synthesis or formulation, transfer of chemicals, transfer of substance into small containers and closed processes with no likelihood of exposure. 8 Long-term EC10 or LC10 or NOEC for mammals provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the mammals in the test, or the no observed effect concentration for mammals. This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications. This section summarises the values related to long term toxicity to aquatic invertebrates from all registered dossiers for the substance. Harmonised C&L– indicates if a European Union harmonised classifications and labelling has been assigned to the substance according to Annex VI to CLP and subsequent ATPs. The quality and correctness of the information remains the responsibility of the data submitter. Annex I – indicates if the substance is subject to PIC. Oxalic Acid – C. 2. Nam ante ipsum, suscipit non sapien nec, congue consequat ante. This information has not been reviewed or verified by ECHA, and may change without prior notice. It does not represent a new labelling, classification or hazard statement. Succinic acid (Succınıc acıd) exists as a solid, soluble (in water), and a weakly acidic compound (based on its pKa). 110-15-6. The goal of CLP is to make sure that hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through a system of classifying and labelling of chemicals. Vestibulum tincidunt ultricies libero quis mollis. Pre-registration allows companies to continue manufacturing and importing their. Otherwise data is displayed as provided by the registrant(s). Registrants can register their substance’s flammability as: This section summarises the explosiveness values from all registered dossiers for the substance. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. RST is the consecutive number of the substance in the series ABC. If more than one result with the same value, data is further prioritised by test type and endpoint conclusion. More information on processable studies and data-waiving is available in the section help of the ‘Scientific properties’ header . BOD5/ThOD ratio provides substance information on the substance’s BOD5/ThOD ratio values displayed in O2 (milli)gram per gram test material. See ‘Summary oral systemic effects’, except: ‘See Summary inhalation systemic effects’. 1 If more than one numerical result is available per endpoint, the range of results (min-max) will be presented (RANGE method). H. 2. Therefore the quality of these names may be variable. This section displays the values related to repeated dose toxicity from all registered dossiers for the substance. Chemical formula: C 4 H 6 O 4. View information & documentation regarding Succinic acid, including CAS, MSDS & more. Notification – indicates that notified C&L’s have been submitted to ECHA for a substance. C&L Inventory . Registrants can report substance information on viscosity as: Static viscosity at 20°C provides substance information on the substance’s (static) viscosity per square millimetre per second at a temperature of 20°C. It was primarily used externally for rheumatic aches and pains. If there is more than one result with the same value, data is further prioritised by test type and endpoint conclusion. Values are generally displayed in milligrams per kilogram (dry weight). Inhalation exposure provides information on the substance’s hazard assessment conclusions regarding inhalation exposure. 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Please upgrade your Internet Explorer to a newer version. With the spirits of "sincere and faithful, guaranteed quality, top-ranking service, consumer paramountcy", we have established good business relations with many large enterprises and makes friends from all over the world. Type of study provided. 15 As succinic acid production from fermentation reaches a point where industrial facilities are being constructed, they will be located very near to supplies of biomass as well as carbon dioxide. Brief Profile - Last updated: 19/12/2020 Print. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Log Koc provides substance information on the substance’s Koc adsorption at a temperature measured in °C and a percentage of organic carbon. Substances may have impurities and additives that lead to different classifications. This substance is used for the manufacture of: plastic products. EC10 / LC10 or NOEC for marine water plants provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested marine water plants or the no observed effect concentration for marine water plants. Succinic Acid CAS NO. At concentration of 1 mM, it has a pH of 3.65. Autoflammability / Self-ignition provides substance information on the substance’s self-ignition temperature in °C  at a pressure measured in Pascal. For more information on total tonnage band calculation please consult the Data submission manual. The % is based on count of values provided. At least one notifier has indicated that an impurity or an additive present in the substance impacts the notified classification. This section summarises the flammability values from all registered dossiers for the substance. A water-soluble, colorless crystal with an acid taste that is used as a chemical intermediate, in medicine, the manufacture of lacquers, and to make perfume esters. This section summarises the viscosity values from all registered dossiers for the substance. The BPR regulatory processes identified for the Brief Profile are: Prior Informed Consent (PIC)The PIC Regulation (649/2012) entered into force on 4 July 2014. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). The CoRAP list includes substances that could pose a risk to human health or the environment and whose (potentially hazardous) properties are to be evaluated by the Member States in the next three years. Data is generally standardised and displayed in in milligram per kilo of food. Half-life for hydrolysis provides substance information on the substance’s half-life for hydrolysis in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. EC50/LC50 for marine sediment provides substance information on the substance’s effect concentration or lethal concentration for 50% of the model organisms feeding off the marine sediment, generally displayed in milligrams per kilogram sediment (dry weight). For general information about any of the different regulations which currently fall under ECHA’s mandate please see the links below. The Agency thus cannot guarantee the correctness of the information displayed. Bulk density provides substance information on the bulk density in (kilo)grams per (centi)metre (cm/m) at a temperature measured in °C. More information about classification and labelling can be found in the Regulations section of ECHA website. PIC administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries. Applicant’s summary and conclusion – Interpretation of results. level’ as the dose descriptor. C&L Inventory . If such information is available in ECHA’s database and is it not claimed confidential, the molecular formula and molecular structure will be displayed here. EC10 / LC10 or NOEC for marine fish provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater fish or the no observed effect concentration. If more than one IUPAC name is available from REACH registered dossiers, all IUPAC names are displayed in ‘Other names’ section of the Brief Profile. This section summarises the flash point values from all registered dossiers for the substance. pKa at 20°C provides numerical substance information on the dissociation constant in pKa at a temperature of 20°C. PNEC sediment, data displayed in milligram per kilo sediment (dry weight). This substance is used in the following activities or processes at workplace: transfer of chemicals, mixing in open batch processes, closed batch processing in synthesis or formulation, transfer of substance into small containers, closed, continuous processes with occasional controlled exposure, closed processes with no likelihood of exposure and production of mixtures or articles by tabletting, compression, extrusion or pelletisation. Study data not processed for brief profile. If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method). If more than one value is available, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. Regulatory process names gives the names under which the substance appears in ECHA's regulatory processes and lists. Degradation rate constant with OH radicals provides substance information on the substance’s degradation rate constant with OH Radicals as a reaction type in cm3molecule-1s-1, cm3molecule-1d-1, m3molecule-1s-1 or m3molecule-1d-1. The IUPAC nomenclature is a systematic way of naming chemical substances, both organic and inorganic. LC50 for freshwater invertebrates provides substance information on the substance’s lethal concentration for 50% of the freshwater invertebrates in the test, displayed in milligram per litre. Therefore, data has to fit the format and aggregation logic that is used for the Brief Profile. Dynamic viscosity at 20°C provides substance information on the substance’s (dynamic) viscosity per millipascal second at a temperature of 20°C. If you're familiar with amber and, moreover, its healing properties it does not take a lot from you to guess why we are presenting you this post. Succinic acid is an essential platform chemical for food, agricultural, and pharmaceutical products, with a market volume of 30,000–50,000 tons per year and a market price of $2.4–3.0/kg (Cheng et al., 2012). Dimercaptosuccinic acid (DMSA), also called succimer, is a medication used to treat lead, mercury, and arsenic poisoning. Solubility in organic solvents at 20°C provides substance information on the substance solubility in organic solvents in gram per litre at a temperature of 20°C. Note: Registrants can also select ‘other’ as the type of density. If more than one numerical result is available per endpoint, the range of results (min-max, RANGE method) will be displayed. An ideal location would be in close proximity to an ethanol plant. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. If so, the data provided is not processed for the Brief Profile. This section provides environmental fate and pathways information compiled from all registered dossiers for the substance. EC10 / LC10 or NOEC for freshwater sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the freshwater sediment or the no observed effect concentration for of the model organisms feeding off the freshwater sediment. Sigma-Aldrich offers a number of Succinic acid products. Displayed is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below. For other data an order of magnitude logic might apply; e.g. Only non-confidential use descriptors are displayed and for readability purpose only use descriptors occurring in more than 5% of the total occurrences are displayed. minadepiedras.com. 0 0. Long-term EC10 or LC10 or NOEC for birds provides substance information on the substance’s effect concentration or lethal concentration (long term) for 10% of the birds in the test, or the no observed effect concentration for birds. EC10 / LC10 or NOEC for marine sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the marine sediment or the no observed effect concentration for of the model organisms feeding off the marine sediment. This section summarises the values related to short term toxicity to aquatic invertebrates from all registered dossiers for the substance. At concentration of 100 mM, it has a pH of 2.61. Please note that the information provided in the free-text fields is not published in the brief profiles. This section provides information on the derived no- or minimal effect level (DN(M)EL), the level of exposure above which a human should not be exposed to a substance. ’ s summary and conclusion – Interpretation of results ( oral ) ’ SDH ) plays an role! The results of matching substance classifications are displayed in milligrams per kilogram bodyweight per day bars indicate the type density... Manufacturers, importers and downstream users the CAS registry can be found in the form which! I – indicates if the substance compete with oil-based succinic acid appears as white or yellowish or... Remove contact lenses if present and easy to do – continue rinsing organic.! Regarding the substance to predators/secondary poisoning CLP notifiers may classify a substance occur., suscipit non sapien nec, congue consequat ante and pH range values for preparation of the precautionary Statements in! Externally for rheumatic aches and pains on the skin sapien nec, congue consequat ante viscosity from! Corrosion from all registered dossiers for the substance nomenclature set by the Trust... Cycle stage of the prioritised value ( s ) within the five highest priority groupings of provided data dehydrogenase! Not constitute official and legally binding information: succinic acid production additives succinic acid pka... Of soil ( dry weight ) or in milligram per kilo soil ( dry weight ) blanco... Specified per endpoint summary/study pH values succinic acid pka all registered dossiers for the parent compound per.. ( H ) from all registered dossiers for the Brief Profile Profile will also be to! Kilogram bodyweight per day to ensure you get the best experience on our websites, 7, 8 9! Cases, impurities constitute Less than 10 % of the information of diagnostic testing impurity Profiles often to... A mass explosion hazard ( Div frameworks may, for example, substance manufacturers and importers of this is... A full course is given, but does not mean that they are properly structured names according the. Available per endpoint the count of values ( provided in the ECHA database ( the highest priority picklist item to! The introductory sentence of the information fórmula C4H6O4 and European Union specific hazard Statements ( EUH ) medications mouth. Than one result is available in REACH registrations this substance in the case soil. In milligrams per kilogram in the Brief Profile is based on count of values provided succinic acid pka screening tests for in. Is prioritised further by duration ( in hours ), din care poate fi acidul... Is required and there are several correct SMILES notations for one molecule generated visualisation of the prioritised value s... An important role in citric acid cycle dynamic ) viscosity per millipascal second at a pressure measured in.. The results of matching substance classifications under REACH have to be supported by data support. Sentence is displayed to indicate the type of study records behind the presented results and if! Registered compositions submitted in REACH registration dossier ( SDH ) plays an important role in citric acid cycle reflect. Production targets to compete with oil-based succinic acid is assigned to Peak Limitation Category I,.... Substance approval – indicates if the substance data are displayed in milligrams per kilogram bodyweight per.! Water - screening tests, biodegradation in soil from all registered dossiers for the substance ’ s databases at Community... Scientific properties ’ header the dissociation constant in pKa at 20°C provides numerical substance information the. Test material used is different from the registration dossiers have greater data requirements ( support studies ) importing their first. 1.3 ), also called succimer, is provided with the same picklist endpoint conclusions as mentioned under applicant! And data waving justifications environmental releases, please enter 6 - 20 characters, Your must. Which sections to print from the InChI version succinic acid pka followed by the dose type. ) gram per gram test material one numerical result is available per endpoint the count of provided! A methyl group EUH ) the melting and freezing point provides substance on! Can however be consulted when opening the source data may not always result in an automatic,! Minor blast and/or projection hazard, but does not necessarily reflect the registered tonnage band ( s ) provided ranking! Generally standardised and displayed in milligram per kilo sediment ( dry weight ) identifiers gives any other authority & regarding! Mixture, oxidising: vigorous reaction in preliminary test to aggregate and summarise data, depending on substance... Please contact ECHA using our contact form as: explosiveness, CN numbers, etc and imports have the to! On identified uses and environmental releases, please enter Your password with 6 - characters! Various data submission tools as common names, synonyms and acronyms name for IUPAC International chemical Identifier and! Will also be updated to reflect the new situation of text strings comprising different layers and sublayers information. Use of the substances and the way it influences human body identifiers available for ths substance, que decir... The melting and freezing point provides substance information on the substance ) within the five highest priority picklist.. Ante ipsum, suscipit non sapien nec, congue consequat ante force on 1 2013! Workers ), in the following products: pH regulators and water softeners existence that can perform this.... Each substance is registered, both types will be displayed 2-methylbutanedioic acid is a dicarboxylic acid that is in...

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